Liver Disease And Obesity Linked To Defective Fat Sensor

London researchers have discovered that a fault in a protein that functions as a fat sensor may be one cause of obesity and liver disease. The protein GPR120 is normally found in the gut, liver and fat tissue and responds to unsaturated fatty acids, however mice deficient in the protein were more likely to develop obesity and liver disease.

“Being overweight is not always unhealthy if you can make more fat cells to store fat,” said Professor Philippe Froguel, of the School of Public Health at Imperial College London. “Some people seem to be unable to do this, and instead they deposit fat around their internal organs, which is very unhealthy. Our study suggests that in both mice and humans, defects in GPR120 combined with a high-fat diet greatly increase the risk of this unhealthy pattern of obesity. We think GPR120 could be a useful target for new drugs to treat obesity and liver diseases.” Professor Froguel was lead author in the study which was done by researchers from France and Japan, as well as from the United Kingdom.

Source: sciencedaily.com

Eating Disorder Self Test. Take the EAT-26 self test to see if you might have eating disorder symptoms that might require professional evaluation. All answers are confidential.

Find a Treatment Facility Near You

Click on a state below to find eating disorder treatment options that could be right for you.

The information provided on EatingDisorders.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her health professional. This information is solely for informational and educational purposes and we encourage all visitors to see a licensed physician if they believe that they have an eating disorder. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Neither the owners or employees of EatingDisorders.com nor the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Always speak with your primary health care provider before engaging in any form of self treatment. Please see our Legal Statement for further information.

Copyright © 2008-2017 EatingDisorders.com.
Company Information

© 2017 EatingDisorders.com. All rights reserved. Use of this site constitutes acceptance of EatingDisorders.com's terms of service and privacy policy. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider.