Anti Epileptic Drugs Potential Eating Disorder Treatment
Several antiepileptic drugs are playing an emerging role in management of some eating disorders, according to researchers at the University of Cincinnati (UC) and the Lindner Center of HOPE.
Many AEDs have effects on neural systems that are important in regulating eating and weight control, the authors say. Topiramate, along with zonisamide and felbamate, are associated with weight loss and decreased appetite.
In randomized, placebo-controlled trials, topiramate was found to be effective in the treatment of bulimia nervosa and binge-eating disorder, and zonisamide was found to be effective in the treatment of binge-eating disorder. In addition, carbamazepine was effective for bulimia nervosa and phenytoin for binge/compulsive eating.